Just saw two recently published papers:
Liu et al. 2012. Deciphering the Signature of Selective Constraints on Cancerous Mitochondrial Genome. Molecular Biology and Evolution, 29 (4): 1255-1261.
Ericson et al. 2012. Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer. PLoS Genetics, 8(6): e1002689.
I wonder if mtDNA mutations are increased or decreased in cancer cells compared to their adjacent normal cells, as the two articles gave contradictory conclusions. Of course I should read through them thoroughly before saying anything new.
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